Every person metabolizes different and takes our products for a variety of reasons. We believe in micro-dosing to determine what works best for you. Start with a small amount and adjust to find a dose that is effective for you. There is no defined limit to how much you can ingest in a day, but please proceed with caution if taking a large amount. It is always best to talk with your physician before starting a new dietary supplement. For our vape products, we suggest starting with a few puffs a day, then moving to an as needed basis. Effects last for up to 3 hours.